A list of selected publications.

  • Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks

    Communications Biology, 2023

    Vivek Appadurai, Jonas Bybjerg-Grauholm, Morten Dybdahl Krebs, Anders Rosengren, Alfonso Buil, Andrés Ingason, Ole Mors, Anders D. Børglum, David M. Hougaard, Merete Nordentoft, Preben B. Mortensen, Olivier Delaneau, Thomas Werge & Andrew J. Schork

    Biobanks are awesome for research, but they often use different technologies to collect data over many years. This can make it tricky to combine datasets. In this paper, we looked at how different ways of combining data affect our ability to study complex traits. We found that the methods we use to combine data can have a big impact on our results, and that we need to be especially careful when studying diverse populations.

    Read More

  • Genetic predictors of educational attainment and intelligence test performance predict voter turnout

    Nature Human Behaviour, 2020

    Lene Aarøe, Vivek Appadurai, Kasper M. Hansen, Andrew J. Schork, Thomas Werge, Ole Mors, Anders D. Børglum, David M. Hougaard, Merete Nordentoft, Preben B. Mortensen, Wesley Kurt Thompson, Alfonso Buil, Esben Agerbo & Michael Bang Petersen

    Why do some people vote and others don't? We looked at the genetics of voter turnout and found that it's linked to the same genes that influence educational attainment and intelligence. This suggests that the resources people have for politics, like education and intelligence, play a role in whether they vote.

    Read More

  • Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study

    Molecular Psychiatry, 2020

    Annette Erlangsen, Vivek Appadurai, Yunpeng Wang, Gustavo Turecki, Ole Mors, Thomas Werge, Preben B. Mortensen, Anna Starnawska, Anders D. Børglum, Andrew Schork, Ron Nudel, Marie Bækvad-Hansen, Jonas Bybjerg-Grauholm, David M. Hougaard, Wesley K. Thompson, Merete Nordentoft & Esben Agerbo

    Suicide is a serious problem, and we know that it can run in families. In this study, we looked for specific genes that might be involved in suicide attempts. We found a few promising candidates, and we also found that the genetics of suicide attempts might be different in people with and without mental disorders.

    Read More

  • PhD Thesis

    University of Copenhagen, 2021

    Vivek Appadurai

    My PhD thesis is all about how to use large, complex biobanks to study complex traits like human behavior. I looked at the challenges of combining data from different sources, and I developed new methods for analyzing this type of data. My goal was to help researchers get the most out of these amazing resources.

    Read More